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Buy Day today: Neutral (53) Mixed market breadth · no major macro event

Madrigal Pharmaceuticals Inc (MDGL)

Healthcare Biotechnology
467.30 $
Closing price · As of: 31. Jul 2026
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Basics

Market Cap
10.9$B
Shares Outstanding
23Mio.
Float
60.7%
Beta
-1.1

Performance

Perf. 1M
2.20%
Perf. 3M
3.30%
Perf. 6M
-12.50%
YTD Performance (%)
-11.80%
52-Week-High Distance
-16.5%

Valuation

P/E
Forward P/E
666.7
PEG
P/B
19.8
P/S
8.5
EV/EBITDA
-8.3
Price/FCF

Profitability

Gross Margin
93.1%
EBIT Margin
-29.8%
Net Margin
-27.3%
Return on Equity
-49.4%
Return on Assets
-17.6%

Balance Sheet & Safety

Equity Ratio
44.3%
Debt/Equity
0.6
Altman Z″
1.25
weak
Piotroski
2 out of 9

Growth

Sales Growth Last Quarter
126.80%
EPS Growth Last Quarter
0.00%
Sales Growth (Year)
432.05%
Forward Sales Growth
47.52%
Forward EPS Growth
289.80%

Quality & Screener

Stage
2
RS Rating
68
EPS Rating
42
weak
Piotroski
2 out of 9
Fundamental Rating
B (57 out of 100)
Altman Z″
1.25

AI Rating

Not yet rated — we only show a category once an SEC-backed file with at least two cited passages is available. How the Rating Is Built

Highlighted are things our editorial team noticed: green = stands out as strong, red = deserves a closer look. No single metric is a verdict on its own — always read it in context.

Sales Per Quarter ($M)
2024: Q4 · 103.3 $M Q4 2025: Q1 · 137.2 $M Q1 2025: Q2 · 212.8 $M Q2 2025: Q3 · 287.3 $M Q3 2025: Q4 · 321.1 $M Q4 2026: Q1 · 311.3 $M Q1 2026: Q2 · 364.3 $M Q2
Earnings Per Share Per Quarter ($)
2024: Q4 · -2.71 $ Q4 2025: Q1 · -2.61 $ Q1 2025: Q2 · -1.50 $ Q2 2025: Q3 · -4.01 $ Q3 2025: Q4 · -2.03 $ Q4 2026: Q1 · -3.25 $ Q1 2026: Q2 · -1.99 $ Q2
Net Margin Per Quarter (%)
2024: Q4 · -57.5 % Q4 2025: Q1 · -53.4 % Q1 2025: Q2 · -19.9 % Q2 2025: Q3 · -39.8 % Q3 2025: Q4 · -18.2 % Q4 2026: Q1 · -30.3 % Q1 2026: Q2 · -15.9 % Q2
Operating Cash Flow Per Quarter ($M)
2024: Q4 · -104.5 $M Q4 2025: Q1 · -88.9 $M Q1 2025: Q2 · -47.1 $M Q2 2025: Q3 · 79.8 $M Q3 2025: Q4 · -133.5 $M Q4 2026: Q1 · -167.4 $M Q1 2026: Q2 · 23.3 $M Q2
Free Cash Flow Per Quarter ($M)
2024: Q4 · -104.7 $M Q4 2025: Q1 · -88.9 $M Q1 2025: Q2 · -47.1 $M Q2 2025: Q3 · 79.0 $M Q3 2025: Q4 · -133.1 $M Q4 2026: Q1 · -171.3 $M Q1 2026: Q2 · 19.0 $M Q2
Sales Growth vs. Year-Ago Quarter (%)
2024: Q4 · 13,318.2 % Q4 2025: Q2 · 1,353.8 % Q2 2025: Q3 · 362.0 % Q3 2025: Q4 · 210.8 % Q4 2026: Q1 · 126.8 % Q1 2026: Q2 · 71.2 % Q2
EPS Growth vs. Year-Ago Quarter (%)
2026: Q2 · -32.7 % Q2
Price Change in Quarter (%)
2024: Q4 · 45.4 % Q4 2025: Q1 · 7.3 % Q1 2025: Q2 · -8.6 % Q2 2025: Q3 · 51.6 % Q3 2025: Q4 · 27.0 % Q4 2026: Q1 · -10.1 % Q1

Quarterly Figures

Quarterly Figures
Quarter EPS (Earnings Per Share) EPS YoY (%) Sales ($M) Sales YoY (%) Net Margin (%) OCF ($M) FCF ($M)
2024: Q4 -2.71 103 13,318.20 -57.50 -105 -105
2025: Q1 -2.61 137 -53.40 -89 -89
2025: Q2 -1.50 213 1,353.80 -19.90 -47 -47
2025: Q3 -4.01 287 362.00 -39.80 80 79
2025: Q4 -2.03 321 210.80 -18.20 -134 -133
2026: Q1 -3.25 311 126.80 -30.30 -167 -171
2026: Q2 -1.99 -32.70 364 71.20 -15.90 23 19
What Do These Terms Mean?
EPS (Earnings Per Share):
Quarterly profit divided by the total share count — how much of the profit works out to a single share.
YoY (Year over Year):
Change versus the same quarter a year ago — this is how you compare without seasonal distortion (e.g. the holiday shopping season).
Sales:
All revenue for the quarter, before any costs are deducted — the top line of the income statement.
Net Margin:
What percentage of sales is left over as profit in the end. Negative means the company is posting a loss.
OCF (Operating Cash Flow):
The cash that actually flows into the till from the core business during the quarter — harder to dress up than book profit.
FCF (Free Cash Flow):
Operating cash flow minus capital expenditures — the money that's genuinely free to use, say for paying down debt, buybacks, or dividends.

About the Company

Madrigal Pharmaceuticals, Inc. ist ein biopharmazeutisches Unternehmen, das sich auf die Bereitstellung neuartiger Therapeutika für die metabolisch bedingte Steatohepatitis (MASH) in den USA konzentriert.

Employees915
HeadquartersWest Conshohocken, PA
Websitemadrigalpharma.com
IPO Date6. Feb 2007
Next Earnings4. Aug 2026

Management

Management
Name Title Birth Year
William J. Sibold CEO, President & Director 1966
Rebecca A. Taub M.D. Founder, Senior Scientific & Medical Advisor and Director 1952
Mardi C. Dier Executive VP & CFO 1964
Shannon Kelley Executive VP, Chief Legal Officer & Corporate Secretary 1975
Carole Huntsman Executive VP & Chief Commercial Officer 1965
David Soergel M.D. Executive VP & Chief Medical Officer 1968
Mark Underwood Executive Vice President of Business Planning & Operations
Rita Thakkar Senior VP & Chief Accounting Officer 1974
Ronald Filippo Executive VP & Chief Information Officer
Tina E. Ventura Chief Investor Relations Officer

Executives per the latest required filings; titles kept in their original language. Source: fundamental data.

Insider Transactions

Insider Transactions
Date Person Role Type Shares Price Value
20. Jul 2026 Sibold William John President and CEO Sell 280 555.05 155,414
20. Jul 2026 Sibold William John President and CEO Sell 1 550.72 551
20. Jul 2026 Sibold William John President and CEO Sell 153 550.01 84,152
20. Jul 2026 Sibold William John President and CEO Sell 47 548.87 25,797
20. Jul 2026 Sibold William John President and CEO Sell 680 547.70 372,435
20. Jul 2026 Sibold William John President and CEO Sell 269 547.08 147,164
20. Jul 2026 Sibold William John President and CEO Sell 275 545.71 150,070
20. Jul 2026 Sibold William John President and CEO Sell 545 544.71 296,869
20. Jul 2026 Sibold William John President and CEO Sell 110 543.79 59,817
20. Jul 2026 Sibold William John President and CEO Sell 140 542.75 75,984

Reportable transactions by officers and major shareholders from SEC Form 4 filings. "Other" includes things like stock grants and option exercises without a buy/sell character.

View all insider transactions →

Chart

Interactive price chart (TradingView).

Data as of: July 31, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)

Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.

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