Karyopharm Therapeutics Inc (KPTI)
Who owns Karyopharm Therapeutics Inc (KPTI)? This page shows the largest institutions and funds, the ownership structure and the latest insider transactions. 65.4% of the shares are freely tradable; institutional investors hold 83.7%.
Ownership Structure
Largest Shareholders
Institutions
| Name | Stake (%) | Shares | Change (%) | Date |
|---|---|---|---|---|
| COMMODORE CAPITAL LP | 8.60 | 1,950,000 | +0.0 | 03/31/2026 |
| RA Capital Management, LLC | 8.46 | 1,917,354 | +0.0 | 03/31/2026 |
| Adage Capital Partners Gp LLC | 7.97 | 1,806,322 | +328.7 | 03/31/2026 |
| T. Rowe Price Investment Management,Inc. | 6.80 | 1,542,090 | -25.8 | 03/31/2026 |
| The Goldman Sachs Group Inc | 4.18 | 947,579 | +0.0 | 03/31/2026 |
| Avidity Partners Management LP | 4.09 | 927,482 | +589.2 | 03/31/2026 |
| Catalio Capital Management, LP | 3.96 | 897,709 | +527.8 | 03/31/2026 |
| Squadron Capital Management LLC | 3.31 | 750,000 | +0.0 | 03/31/2026 |
| Vanguard Capital Management, LLC | 3.26 | 739,745 | +0.0 | 03/31/2026 |
| Ikarian Capital, LLC | 3.24 | 733,435 | +34.7 | 03/31/2026 |
Largest reported positions according to regulatory filings; stake as a percentage of shares outstanding, change versus the previous filing. Source: fundamentals data.
Insider Transactions
| Date | Person | Role | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| 28. Jul 2026 | Poulton Stuart | EVP, Chief Development Officer | Sell | 189 | 7.10 | 1,342 |
| 21. Apr 2026 | Reshma Rangwala | EVP | Sell | 449 | 8.94 | 4,014 |
Reportable transactions by officers and major shareholders from SEC Form 4 filings. "Other" includes things like stock grants and option exercises without a buy/sell character.
View all insider transactions →Data as of: July 31, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)
Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.