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Buy Day today: Poor Neutral (49) Good Mixed market breadth · no major macro event

Pliant Therapeutics Inc (PLRX)

Healthcare Biotechnology
1.10 $
Closing price · As of: 20. Jul 2026
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Basics

Market Cap
0.1Mrd. $
Shares Outstanding
62Mio.
Float
91.4%
Beta
1.2

Performance

Perf. 1M
-8.00%
Perf. 3M
-1.70%
Perf. 6M
-6.50%
YTD Performance (%)
-4.90%
52-Week-High Distance
-42.1%

Valuation

P/E
Forward P/E
0.0
PEG
P/B
0.4
P/S
EV/EBITDA
-2.5
Price/FCF

Profitability

Gross Margin
EBIT Margin
Net Margin
0.0%
Return on Equity
-53.6%
Return on Assets
-25.8%

Balance Sheet & Safety

Equity Ratio
Debt/Equity
0.2
warning zone
Altman Z
-4.57
Piotroski
5 von 9

Growth

Sales Growth Last Quarter
0.00%
EPS Growth Last Quarter
0.00%
Sales Growth (Year)
-100.00%
Forward Sales Growth
0.00%
Forward EPS Growth
33.10%

Quality & Screener

Stage
4
RS Rating
22
EPS Rating
42
Piotroski
5 von 9
Fundamental Rating
D (-31 von 100)
warning zone
Altman Z
-4.57

AI Rating

Neutral

In den ausgewerteten SEC-Berichten von Pliant Therapeutics (4 Quartalsberichte 10-Q und 2 Jahresberichte 10-K) findet sich kein wesentlicher KI-Bezug: Das Geschäft ist die klinische Entwicklung integrin-basierter Wirkstoffe (Lead PLN-101095, ein oraler Integrin-Hemmer gegen solide Tumoren); KI ist weder Umsatzquelle noch belegter operativer Baustein noch ein konkret aufs eigene Modell bezogenes Geschäftsrisiko. Die Wirkstoff-Entdeckungsplattform wird als »proprietäre Bibliothek von über 15.000 Integrin-Bindemolekülen« beschrieben, ohne KI oder maschinelles Lernen zu erwähnen. Die einzige Nennung von »artificial intelligence« ist eine generische regulatorische Randbemerkung, dass die US-Arzneimittelbehörde FDA neue Richtlinien zum KI-Einsatz bei der Prüfung von Zulassungsanträgen angekündigt habe — kein Bezug zu Pliants eigenem Geschäftsmodell.

View the full file — quotes, sources, reviewed filings

Highlighted are things our editorial team noticed: green = stands out as strong, red = deserves a closer look. No single metric is a verdict on its own — always read it in context.

Sales Per Quarter ($M)
2024: Q4 · 2.3 Mio. $ Q4 2025: Q1 · 0.0 Mio. $ Q1 2025: Q2 · 0.0 Mio. $ Q2 2025: Q3 · 0.0 Mio. $ Q3 2025: Q4 · 0.0 Mio. $ Q4 2026: Q1 · 0.0 Mio. $ Q1
Earnings Per Share Per Quarter ($)
2024: Q4 · -0.80 $ Q4 2025: Q1 · -0.91 $ Q1 2025: Q2 · -0.70 $ Q2 2025: Q3 · -0.42 $ Q3 2025: Q4 · -0.38 $ Q4 2026: Q1 · -0.32 $ Q1
Net Margin Per Quarter (%)
2024: Q4 · -2,190.8 % Q4
Operating Cash Flow Per Quarter ($M)
2024: Q4 · -47.7 Mio. $ Q4 2025: Q1 · -48.9 Mio. $ Q1 2025: Q2 · -40.6 Mio. $ Q2 2025: Q3 · -21.1 Mio. $ Q3 2025: Q4 · -17.8 Mio. $ Q4 2026: Q1 · -19.2 Mio. $ Q1
Free Cash Flow Per Quarter ($M)
2024: Q4 · -47.9 Mio. $ Q4 2025: Q1 · -49.1 Mio. $ Q1 2025: Q2 · -40.7 Mio. $ Q2 2025: Q3 · -21.1 Mio. $ Q3 2025: Q4 · -17.8 Mio. $ Q4 2026: Q1 · -19.2 Mio. $ Q1
Sales Growth vs. Year-Ago Quarter (%)
2024: Q4 · -53.1 % Q4 2025: Q4 · -100.0 % Q4
Price Change in Quarter (%)
2024: Q4 · 17.5 % Q4 2025: Q1 · -89.7 % Q1 2025: Q2 · -14.1 % Q2 2025: Q3 · 27.6 % Q3 2025: Q4 · -17.6 % Q4 2026: Q1 · 3.3 % Q1

Quarterly Figures

Quarterly Figures
Quarter EPS (Earnings Per Share) EPS YoY (%) Sales ($M) Sales YoY (%) Net Margin (%) OCF ($M) FCF ($M)
2024: Q4 -0.80 2 -53.10 -2,190.80 -48 -48
2025: Q1 -0.91 0 -49 -49
2025: Q2 -0.70 0 -41 -41
2025: Q3 -0.42 0 -21 -21
2025: Q4 -0.38 0 -100.00 -18 -18
2026: Q1 -0.32 0 -19 -19
What Do These Terms Mean?
EPS (Earnings Per Share):
Quarterly profit divided by the total share count — how much of the profit works out to a single share.
YoY (Year over Year):
Change versus the same quarter a year ago — this is how you compare without seasonal distortion (e.g. the holiday shopping season).
Sales:
All revenue for the quarter, before any costs are deducted — the top line of the income statement.
Net Margin:
What percentage of sales is left over as profit in the end. Negative means the company is posting a loss.
OCF (Operating Cash Flow):
The cash that actually flows into the till from the core business during the quarter — harder to dress up than book profit.
FCF (Free Cash Flow):
Operating cash flow minus capital expenditures — the money that's genuinely free to use, say for paying down debt, buybacks, or dividends.

About the Company

Pliant Therapeutics, Inc., ein biopharmazeutisches Unternehmen in der klinischen Phase, konzentriert sich auf die Entdeckung und Entwicklung integrinbasierter Therapeutika zur Behandlung solider Tumore.

Employees49
HeadquartersSouth San Francisco, CA
Websitepliantrx.com
IPO Date3. Jun 2020
Next Earnings6. Aug 2026

Management

Management
Name Title Birth Year
Bernard Coulie M.B.A., M.D., Ph.D. President, CEO & Director 1966
Keith Lamont Cummings M.B.A., M.D. Chief Financial Officer 1977
Minnie Kuo Chief Operating Officer 1981
Rik Derynck Ph.D. Scientific Founder & Member of Scientific Advisory Board
Dean Sheppard M.D. Scientific Founder & Member of Scientific Advisory Board
Hal Chapman M.D. Scientific Founder & Member of Scientific Advisory Board
Delphine Imbert Ph.D. Chief Technical Officer
Christopher S. Keenan Vice President of Investor Relations & Corporate Communications
Monica Sandberg Ph.D. Vice President, Regulatory & Compliance
Lily Cheung Chief Human Resources Officer 1973

Executives per the latest required filings; titles kept in their original language. Source: fundamental data.

Chart

Interactive price chart (TradingView).

Data as of: July 20, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)

Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.

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