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Buy Day today: Poor Neutral (49) Good Mixed market breadth · no major macro event

Krystal Biotech Inc (KRYS)

Healthcare Biotechnology
339.20 $
Closing price · As of: 20. Jul 2026
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This stock currently matches 21 of our scanner strategies — each hit links to the scanner.

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Basics

Market Cap
10.7Mrd. $
Shares Outstanding
30Mio.
Float
79.4%
Beta
0.5

Performance

Perf. 1M
21.90%
Perf. 3M
54.10%
Perf. 6M
50.50%
YTD Performance (%)
38.00%
52-Week-High Distance
-0.7%

Valuation

P/E
49.3
Forward P/E
49.5
PEG
P/B
8.3
P/S
25.8
EV/EBITDA
55.3
Price/FCF
45.3

Profitability

Gross Margin
94.2%
EBIT Margin
46.1%
Net Margin
53.9%
Return on Equity
19.9%
Return on Assets
9.0%

Balance Sheet & Safety

Equity Ratio
91.4%
Debt/Equity
0.01
fortress balance sheet
Altman Z
19.80
Piotroski
7 von 9

Growth

Sales Growth Last Quarter
31.90%
EPS Growth Last Quarter
52.50%
Sales Growth (Year)
33.94%
Forward Sales Growth
29.01%
Forward EPS Growth
21.50%

Quality & Screener

Stage
2
Top 10%
RS Rating
91
EPS Rating
78
Piotroski
7 von 9
Fundamental Rating
A (+60 von 100)
fortress balance sheet
Altman Z
19.80

AI Rating

Uses AI

Krystal Biotech verkauft keine KI — das Kerngeschäft ist die zugelassene Gentherapie VYJUVEK gegen die Hautkrankheit Epidermolysis bullosa. Der Geschäftsbericht (10-K 2025) belegt jedoch operativen KI-Einsatz: Das Unternehmen hat nach eigener Angabe „in begrenzten Fällen" KI-Plattformen für konkrete geschäftliche Zwecke eingeführt und will KI nutzen, um die Entdeckung und Entwicklung neuer Produktkandidaten zu beschleunigen und die Fertigung zu optimieren. Damit ist KI ein internes Effizienz-Werkzeug (Kategorie „nutzt"), keine eigenständige Umsatzquelle (das schließt „verkauft" aus) und kein konkret gegen das eigene Geschäftsmodell gerichtetes Existenzrisiko (die AI-Risk-Factor-Passage bleibt allgemeine Boilerplate, das schließt „bedroht" aus).

View the full file — quotes, sources, reviewed filings
„As with many technological innovations, AI presents opportunities, risks and challenges that could impact our business... we have adopted and integrated in limited situations artificial intelligence platforms for limited specific business uses and may adopt and integrate additional AI platforms and/or tools into our business."

Wie bei vielen technologischen Innovationen bietet KI Chancen, Risiken und Herausforderungen, die unser Geschäft beeinflussen könnten... wir haben in begrenzten Fällen Plattformen der Künstlichen Intelligenz für begrenzte, konkrete geschäftliche Zwecke eingeführt und integriert und könnten weitere KI-Plattformen und/oder -Werkzeuge in unser Geschäft integrieren.

10-K · 2026-02-17 · View SEC filing
„Harnessing AI's potential may enable us to speed up the discovery and development of new product candidates, optimize our manufacturing processes, and drive efficiencies."

Das Potenzial der KI zu nutzen, könnte es uns ermöglichen, die Entdeckung und Entwicklung neuer Produktkandidaten zu beschleunigen, unsere Fertigungsprozesse zu optimieren und Effizienzen zu heben.

10-K · 2026-02-17 · View SEC filing

Rated on July 10, 2026 · How the Rating Is Built

Highlighted are things our editorial team noticed: green = stands out as strong, red = deserves a closer look. No single metric is a verdict on its own — always read it in context.

Sales Per Quarter ($M)
2024: Q4 · 91.1 Mio. $ Q4 2025: Q1 · 88.2 Mio. $ Q1 2025: Q2 · 96.0 Mio. $ Q2 2025: Q3 · 97.8 Mio. $ Q3 2025: Q4 · 107.1 Mio. $ Q4 2026: Q1 · 116.4 Mio. $ Q1
Earnings Per Share Per Quarter ($)
2024: Q4 · 1.52 $ Q4 2025: Q1 · 1.20 $ Q1 2025: Q2 · 1.29 $ Q2 2025: Q3 · 2.66 $ Q3 2025: Q4 · 1.72 $ Q4 2026: Q1 · 1.83 $ Q1
Net Margin Per Quarter (%)
2024: Q4 · 49.9 % Q4 2025: Q1 · 40.5 % Q1 2025: Q2 · 39.9 % Q2 2025: Q3 · 81.2 % Q3 2025: Q4 · 48.0 % Q4 2026: Q1 · 48.1 % Q1
Operating Cash Flow Per Quarter ($M)
2024: Q4 · 52.8 Mio. $ Q4 2025: Q1 · 31.0 Mio. $ Q1 2025: Q2 · 52.7 Mio. $ Q2 2025: Q3 · 39.7 Mio. $ Q3 2025: Q4 · 77.5 Mio. $ Q4 2026: Q1 · 80.4 Mio. $ Q1
Free Cash Flow Per Quarter ($M)
2024: Q4 · 52.0 Mio. $ Q4 2025: Q1 · 24.8 Mio. $ Q1 2025: Q2 · 50.8 Mio. $ Q2 2025: Q3 · 38.0 Mio. $ Q3 2025: Q4 · 75.4 Mio. $ Q4 2026: Q1 · 73.2 Mio. $ Q1
Sales Growth vs. Year-Ago Quarter (%)
2024: Q4 · 116.3 % Q4 2025: Q1 · 94.9 % Q1 2025: Q2 · 36.6 % Q2 2025: Q3 · 16.6 % Q3 2025: Q4 · 17.5 % Q4 2026: Q1 · 31.9 % Q1
EPS Growth vs. Year-Ago Quarter (%)
2024: Q4 · 404.6 % Q4 2025: Q1 · 3,659.6 % Q1 2025: Q2 · 145.3 % Q2 2025: Q3 · 192.7 % Q3 2025: Q4 · 12.8 % Q4 2026: Q1 · 53.3 % Q1
Price Change in Quarter (%)
2024: Q4 · -13.9 % Q4 2025: Q1 · 15.1 % Q1 2025: Q2 · -23.8 % Q2 2025: Q3 · 28.4 % Q3 2025: Q4 · 39.7 % Q4 2026: Q1 · 4.8 % Q1

Quarterly Figures

Quarterly Figures
Quarter EPS (Earnings Per Share) EPS YoY (%) Sales ($M) Sales YoY (%) Net Margin (%) OCF ($M) FCF ($M)
2024: Q4 1.52 404.60 91 116.30 49.90 53 52
2025: Q1 1.20 3,659.60 88 94.90 40.50 31 25
2025: Q2 1.29 145.30 96 36.60 39.90 53 51
2025: Q3 2.66 192.70 98 16.60 81.20 40 38
2025: Q4 1.72 12.80 107 17.50 48.00 78 75
2026: Q1 1.83 53.30 116 31.90 48.10 80 73
What Do These Terms Mean?
EPS (Earnings Per Share):
Quarterly profit divided by the total share count — how much of the profit works out to a single share.
YoY (Year over Year):
Change versus the same quarter a year ago — this is how you compare without seasonal distortion (e.g. the holiday shopping season).
Sales:
All revenue for the quarter, before any costs are deducted — the top line of the income statement.
Net Margin:
What percentage of sales is left over as profit in the end. Negative means the company is posting a loss.
OCF (Operating Cash Flow):
The cash that actually flows into the till from the core business during the quarter — harder to dress up than book profit.
FCF (Free Cash Flow):
Operating cash flow minus capital expenditures — the money that's genuinely free to use, say for paying down debt, buybacks, or dividends.

About the Company

Krystal Biotech, Inc. ist ein Biotechnologieunternehmen in der kommerziellen Phase, das genetische Medikamente zur Behandlung von Erkrankungen mit hohem ungedecktem medizinischem Bedarf in den USA entdeckt, entwickelt, fertigt und kommerzialisiert.

Employees295
HeadquartersPittsburgh, PA
Websitekrystalbio.com
IPO Date20. Sep 2017
Next Earnings3. Aug 2026

Management

Management
Name Title Birth Year
Krish S. Krishnan M.B.A., M.S. Founder, Chairman, President & CEO 1965
Suma M. Krishnan Founder, President of R&D and Director 1965
Kathryn A. Romano CPA Executive VP & Chief Accounting Officer 1982
John C. Thomas EVP, General Counsel & Corporate Secretary 1974
John Karakkal Vice President of North American Sales & Marketing
Stephane Paquette Ph.D. Senior Vice President of Corporate Development
Josh Suskin Senior Director & Head of US Human Resources
Laurent Goux Executive VP & Head of International 1975
David Chien M.D. Senior Vice President of Clinical Development
Christine Wilson Senior VP & Head of US Commercial

Executives per the latest required filings; titles kept in their original language. Source: fundamental data.

Chart

Interactive price chart (TradingView).

Data as of: July 20, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)

Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.

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