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Buy Day today: Poor Neutral (49) Good Mixed market breadth · no major macro event

Alnylam Pharmaceuticals Inc (ALNY)

Healthcare Biotechnology
272.70 $
Closing price · As of: 20. Jul 2026
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This stock currently matches 6 of our scanner strategies — each hit links to the scanner.

Quality & Balance Sheet
Aktien.Guide
Momentum & Trend

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Basics

Market Cap
38.9Mrd. $
Shares Outstanding
134Mio.
Float
99.6%
Beta
0.3

Performance

Perf. 1M
-3.80%
Perf. 3M
-7.50%
Perf. 6M
-26.70%
YTD Performance (%)
-27.50%
52-Week-High Distance
-40.8%

Valuation

P/E
73.0
Forward P/E
34.1
PEG
0.5
P/B
36.2
P/S
9.1
EV/EBITDA
46.2
Price/FCF
60.7

Profitability

Gross Margin
80.8%
EBIT Margin
23.0%
Net Margin
12.6%
Return on Equity
90.4%
Return on Assets
10.1%

Balance Sheet & Safety

Equity Ratio
21.0%
Debt/Equity
1.2
Altman Z
4.21
Piotroski
7 von 9

Growth

Sales Growth Last Quarter
96.40%
EPS Growth Last Quarter
0.00%
Sales Growth (Year)
65.19%
Forward Sales Growth
30.19%
Forward EPS Growth
44.80%

Quality & Screener

Stage
4
RS Rating
17
EPS Rating
42
Piotroski
7 von 9
Fundamental Rating
A (+53 von 100)
Altman Z
4.21

AI Rating

Not yet rated — we only show a category once an SEC-backed file with at least two cited passages is available. How the Rating Is Built

Sales Per Quarter ($M)
2024: Q4 · 593.2 Mio. $ Q4 2025: Q1 · 594.2 Mio. $ Q1 2025: Q2 · 773.7 Mio. $ Q2 2025: Q3 · 1,249.0 Mio. $ Q3 2025: Q4 · 1,097.0 Mio. $ Q4 2026: Q1 · 1,167.2 Mio. $ Q1
Earnings Per Share Per Quarter ($)
2024: Q4 · -0.65 $ Q4 2025: Q1 · -0.44 $ Q1 2025: Q2 · -0.51 $ Q2 2025: Q3 · 1.83 $ Q3 2025: Q4 · 1.37 $ Q4 2026: Q1 · 1.49 $ Q1
Net Margin Per Quarter (%)
2024: Q4 · -14.1 % Q4 2025: Q1 · -9.7 % Q1 2025: Q2 · -8.6 % Q2 2025: Q3 · 20.1 % Q3 2025: Q4 · 17.0 % Q4 2026: Q1 · 17.6 % Q1
Operating Cash Flow Per Quarter ($M)
2024: Q4 · -94.7 Mio. $ Q4 2025: Q1 · -118.3 Mio. $ Q1 2025: Q2 · 153.7 Mio. $ Q2 2025: Q3 · 325.1 Mio. $ Q3 2025: Q4 · 163.6 Mio. $ Q4 2026: Q1 · 70.5 Mio. $ Q1
Free Cash Flow Per Quarter ($M)
2024: Q4 · -103.8 Mio. $ Q4 2025: Q1 · -127.3 Mio. $ Q1 2025: Q2 · 139.4 Mio. $ Q2 2025: Q3 · 313.0 Mio. $ Q3 2025: Q4 · 140.3 Mio. $ Q4 2026: Q1 · 48.7 Mio. $ Q1
Sales Growth vs. Year-Ago Quarter (%)
2024: Q4 · 34.9 % Q4 2025: Q1 · 20.2 % Q1 2025: Q2 · 17.3 % Q2 2025: Q3 · 149.3 % Q3 2025: Q4 · 84.9 % Q4 2026: Q1 · 96.4 % Q1
Price Change in Quarter (%)
2024: Q4 · -14.4 % Q4 2025: Q1 · 14.8 % Q1 2025: Q2 · 20.8 % Q2 2025: Q3 · 39.8 % Q3 2025: Q4 · -12.8 % Q4 2026: Q1 · -16.8 % Q1

Quarterly Figures

Quarterly Figures
Quarter EPS (Earnings Per Share) EPS YoY (%) Sales ($M) Sales YoY (%) Net Margin (%) OCF ($M) FCF ($M)
2024: Q4 -0.65 593 34.90 -14.10 -95 -104
2025: Q1 -0.44 594 20.20 -9.70 -118 -127
2025: Q2 -0.51 774 17.30 -8.60 154 139
2025: Q3 1.83 1,249 149.30 20.10 325 313
2025: Q4 1.37 1,097 84.90 17.00 164 140
2026: Q1 1.49 1,167 96.40 17.60 71 49
What Do These Terms Mean?
EPS (Earnings Per Share):
Quarterly profit divided by the total share count — how much of the profit works out to a single share.
YoY (Year over Year):
Change versus the same quarter a year ago — this is how you compare without seasonal distortion (e.g. the holiday shopping season).
Sales:
All revenue for the quarter, before any costs are deducted — the top line of the income statement.
Net Margin:
What percentage of sales is left over as profit in the end. Negative means the company is posting a loss.
OCF (Operating Cash Flow):
The cash that actually flows into the till from the core business during the quarter — harder to dress up than book profit.
FCF (Free Cash Flow):
Operating cash flow minus capital expenditures — the money that's genuinely free to use, say for paying down debt, buybacks, or dividends.

About the Company

Alnylam Pharmaceuticals, Inc. entdeckt, entwickelt, fertigt und kommerzialisiert Therapeutika auf Basis von RNA-Interferenz in den USA, Europa und international.

CEO Insider Trades (12 Mo.)selling own stock
Employees2,500
HeadquartersCambridge, MA
Websitealnylam.com
IPO Date28. May 2004
Next Earnings30. Jul 2026

Management

Management
Name Title Birth Year
Yvonne L. Greenstreet M.B.A., M.D. CEO & Director 1963
Phillip A. Sharp Ph.D. Co-Founder, Member of the Scientific Advisory Board 1945
Jeffrey V. Poulton M.B.A. CFO & Executive VP 1968
Bryan Andrew Supran J.D. Chief Legal Officer 1970
Pushkal P. Garg M.D. Executive VP & Chief Research & Development Officer 1968
Tolga Tanguler M.B.A. Executive VP & Chief Commercial Officer 1973
Timothy J. Maines Chief Technical Operations & Quality Officer
Kevin Joseph Fitzgerald Ph.D. Executive VP, Chief Scientific Officer and Head of Early Research & Early Development 1968
Piyush Sharma J.D. Chief Ethics & Compliance Officer
Christine Regan Akinc Chief Corporate Communications Officer 1982

Executives per the latest required filings; titles kept in their original language. Source: fundamental data.

Chart

Interactive price chart (TradingView).

Data as of: July 20, 2026 · Source: fundamental data & SEC filings (annual and quarterly reports, 10-K/10-Q)

Note: pure fact-based analysis, not investment advice and not a solicitation to buy or sell. All figures without guarantee.

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